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Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. However, whether granzymes use additional mechanisms to exert their antipathogen activity remains elusive....

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Bibliografiske detaljer
Main Authors: Andrade, Felipe, Fellows, Edward, Jenne, Dieter E, Rosen, Antony, Young, C S H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852776/
https://ncbi.nlm.nih.gov/pubmed/17363894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601650
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