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Rapid activation of CLOCK by Ca(2+)-dependent protein kinase C mediates resetting of the mammalian circadian clock
In mammals, immediate-early transcription of the Period 1 (Per1) gene is crucial for resetting the mammalian circadian clock. Here, we show that CLOCK is a real signalling molecule that mediates the serum-evoked rapid induction of Per1 in fibroblasts through the Ca(2+)-dependent protein kinase C (PK...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852771/ https://ncbi.nlm.nih.gov/pubmed/17347670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400920 |
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