Medical Sequencing at the Extremes of Human Body Mass

Body weight is a quantitative trait with significant heritability in humans. To identify potential genetic contributors to this phenotype, we resequenced the coding exons and splice junctions of 58 genes in 379 obese and 378 lean individuals. Our 96-Mb survey included 21 genes associated with monoge...

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Autores principales: Ahituv, Nadav , Kavaslar, Nihan , Schackwitz, Wendy , Ustaszewska, Anna , Martin, Joel , Hébert, Sybil , Doelle, Heather , Ersoy, Baran , Kryukov, Gregory , Schmidt, Steffen , Yosef, Nir , Ruppin, Eytan , Sharan, Roded , Vaisse, Christian , Sunyaev, Shamil , Dent, Robert , Cohen, Jonathan , McPherson, Ruth , Pennacchio, Len A. 
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Human Genetics 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852707/
https://ncbi.nlm.nih.gov/pubmed/17357083
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