Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals.

Immunoglobulin secretion by plasma cells infiltrating synovial membranes is a prominent feature of RA. Previous analyses of a cDNA library generated from synovium of RA patient BC revealed immunoglobulin kappa light chain transcripts with extensive somatic mutation, frequent N region addition, and u...

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Detalhes bibliográficos
Main Authors: Bridges, S L, Lee, S K, Johnson, M L, Lavelle, J C, Fowler, P G, Koopman, W J, Schroeder, H W
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC185269/
https://ncbi.nlm.nih.gov/pubmed/7635977
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