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Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice.
Hyperglycemia-induced beta-cell dysfunction may be an important component in the pathogenesis of non-insulin-dependent diabetes mellitus. However, most available data in this field were obtained from rodent islets. To investigate the relevance of this hypothesis for human beta-cells in vivo, human p...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
1995
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC185255/ https://ncbi.nlm.nih.gov/pubmed/7635965 |
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