Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice.

Hyperglycemia-induced beta-cell dysfunction may be an important component in the pathogenesis of non-insulin-dependent diabetes mellitus. However, most available data in this field were obtained from rodent islets. To investigate the relevance of this hypothesis for human beta-cells in vivo, human p...

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Publié dans:	J Clin Invest
Auteurs principaux:	Jansson, L, Eizirik, D L, Pipeleers, D G, Borg, L A, Hellerström, C, Andersson, A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118115
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