Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: Neuropathology and behavioral deficits in single- and double-null mice

Complementary interacting molecules on myelin and axons are required for long-term axon-myelin stability. Their disruption results in axon degeneration, contributing to the pathogenesis of demyelinating diseases. Myelin-associated glycoprotein (MAG), a minor constituent of central and peripheral ner...

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Bibliographic Details
Main Authors: Pan, Baohan, Fromholt, Susan E., Hess, Ellen J., Crawford, Thomas O., Griffin, John W., Sheikh, Kazim A., Schnaar, Ronald L.
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852502/
https://ncbi.nlm.nih.gov/pubmed/15953602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2005.04.017
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