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Dietary supplementation with uridine-5′-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat

The biosynthesis of brain membrane phosphatides, e.g., phosphatidylcholine (PtdCho), may utilize three circulating compounds: choline, uridine (a precursor for UTP, CTP, and CDP-choline), and a PUFA (e.g., docosahexaenoic acid); moreover oral administration of the uridine source uridine-5′-monophosp...

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Detalhes bibliográficos
Main Authors: Wang, Lei, Albrecht, Meredith A., Wurtman, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852434/
https://ncbi.nlm.nih.gov/pubmed/17184749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.11.048
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