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Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

Protein kinases are critical to cellular signalling and post-translational gene regulation, but their biological substrates are difficult to identify. We show that cyclin-dependent kinase (CDK) consensus motifs are frequently clustered in CDK substrate proteins. Based on this, we introduce a new com...

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Hlavní autoři: Moses, Alan M, Hériché, Jean-Karim, Durbin, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852407/
https://ncbi.nlm.nih.gov/pubmed/17316440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-2-r23
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