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A Cell-Based Model Exhibiting Branching and Anastomosis during Tumor-Induced Angiogenesis

This work describes the first cell-based model of tumor-induced angiogenesis. At the extracellular level, the model describes diffusion, uptake, and decay of tumor-secreted pro-angiogenic factor. At the cellular level, the model uses the cellular Potts model based on system-energy reduction to descr...

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Bibliographic Details
Main Authors: Bauer, Amy L., Jackson, Trachette L., Jiang, Yi
Format: Artigo
Language:Inglês
Published: Biophysical Society 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852370/
https://ncbi.nlm.nih.gov/pubmed/17277180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.101501
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