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In Silico Evolved lac Operons Exhibit Bistability for Artificial Inducers, but Not for Lactose

Bistability in the lac operon of Escherichia coli has been widely studied, both experimentally and theoretically. Experimentally, bistability has been observed when E. coli is induced by an artificial, nonmetabolizable, inducer. However, if the lac operon is induced with lactose, the natural inducer...

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Bibliografski detalji
Glavni autori: van Hoek, M. J. A., Hogeweg, P.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578483/
https://ncbi.nlm.nih.gov/pubmed/16877514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077420
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