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In Silico Evolved lac Operons Exhibit Bistability for Artificial Inducers, but Not for Lactose
Bistability in the lac operon of Escherichia coli has been widely studied, both experimentally and theoretically. Experimentally, bistability has been observed when E. coli is induced by an artificial, nonmetabolizable, inducer. However, if the lac operon is induced with lactose, the natural inducer...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1578483/ https://ncbi.nlm.nih.gov/pubmed/16877514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077420 |
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