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Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA

B-cell chronic lymphocytic leukemia (CLL) is characterized by the accumulation of clonal B cells that are resistant to apoptosis as a result of bcl2 oncogene overexpression. Studies were done to determine the mechanism for the up-regulation of bcl-2 protein observed in CD19(+) CLL cells compared wit...

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Bibliografiska uppgifter
Huvudupphovsmän: Otake, Yoko, Soundararajan, Sridharan, Sengupta, Tapas K., Kio, Ebenezer A., Smith, James C., Pineda-Roman, Mauricio, Stuart, Robert K., Spicer, Eleanor K., Fernandes, Daniel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852223/
https://ncbi.nlm.nih.gov/pubmed/17179226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-043257
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