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Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
B-cell chronic lymphocytic leukemia (CLL) is characterized by the accumulation of clonal B cells that are resistant to apoptosis as a result of bcl2 oncogene overexpression. Studies were done to determine the mechanism for the up-regulation of bcl-2 protein observed in CD19(+) CLL cells compared wit...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852223/ https://ncbi.nlm.nih.gov/pubmed/17179226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-043257 |
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