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Vaccine-delivered HIV envelope inhibits CD4(+) T-cell activation, a mechanism for poor HIV vaccine responses

The human immunodeficiency virus (HIV) causes impairment of the immune system in part by targeting CD4(+) T cells for infection and dysfunction. HIV envelope (Env) present on free virions and infected cells causes dysfunction of uninfected bystander CD4(+) T cells via interaction with both CD4 and c...

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書誌詳細
主要な著者: Fernando, Kathy, Hu, Haitao, Ni, Houping, Hoxie, James A., Weissman, Drew
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852208/
https://ncbi.nlm.nih.gov/pubmed/17158230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-038661
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