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Construction of hybrid peptide synthetases by module and domain fusions

Nonribosomal peptide synthetases are modular enzymes that assemble peptides of diverse structures and important biological activities. Their modular organization provides a great potential for the rational design of novel compounds by recombination of the biosynthetic genes. Here we describe the ext...

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Detalhes bibliográficos
Main Authors: Mootz, Henning D., Schwarzer, Dirk, Marahiel, Mohamed A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18522/
https://ncbi.nlm.nih.gov/pubmed/10811885
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