Construction of hybrid peptide synthetases by module and domain fusions
Nonribosomal peptide synthetases are modular enzymes that assemble peptides of diverse structures and important biological activities. Their modular organization provides a great potential for the rational design of novel compounds by recombination of the biosynthetic genes. Here we describe the ext...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811885/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100075897 |
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