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Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury

BACKGROUND: The active form of vitamin D (1,25(OH)(2)D(3)) has been shown to inhibit development of inflammatory bowel disease (IBD) in IL-10 KO mice. Here, the role of the vitamin D receptor (VDR) and 1,25(OH)(2)D(3 )in acute experimental IBD was probed. RESULTS: VDR KO mice were extremely sensitiv...

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Detalles Bibliográficos
Main Authors: Froicu, Monica, Cantorna, Margherita T
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852118/
https://ncbi.nlm.nih.gov/pubmed/17397543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-8-5
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