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Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice

In parallel to imaging studies in humans with Alzheimer's disease (AD), we have mapped brain metabolic activity in transgenic mouse models of AD. Our aim in both is to provide new surrogate markers of progression to help clarify disease mechanisms and rapidly screen candidate therapeutics. Sinc...

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Detalhes bibliográficos
Main Authors: Valla, Jon, Schneider, Lonnie, Reiman, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851938/
https://ncbi.nlm.nih.gov/pubmed/16942758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.07.097
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