Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region.

We have previously demonstrated that sensitivity to interferon is different among hepatitis C virus (HCV) quasispecies simultaneously detected in same individuals and that interferon-resistant HCV quasispecies are selected during the treatment. To determine the genetic basis of their resistance to i...

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Main Authors: Enomoto, N, Sakuma, I, Asahina, Y, Kurosaki, M, Murakami, T, Yamamoto, C, Izumi, N, Marumo, F, Sato, C
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC185192/
https://ncbi.nlm.nih.gov/pubmed/7542279
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