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CXCL1/KC and CXCL2/MIP-2 Are Critical Effectors and Potential Targets for Therapy of Escherichia coli O157:H7-Associated Renal Inflammation

Neutrophilia is a characteristic of hemolytic uremic syndrome caused by Shiga toxin (Stx2)-producing Escherichia coli. However, the role of neutrophils in the toxin-induced renal injury occurring in enterohemorrhagic E. coli infection remains undefined. We report the trafficking of neutrophils to th...

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Библиографические подробности
Главные авторы: Roche, James K., Keepers, Tiffany R., Gross, Lisa K., Seaner, Regina M., Obrig, Tom G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851848/
https://ncbi.nlm.nih.gov/pubmed/17255321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060366
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