Signature-Based Small Molecule Screening Identifies Cytosine Arabinoside as an EWS/FLI Modulator in Ewing Sarcoma

BACKGROUND: The presence of tumor-specific mutations in the cancer genome represents a potential opportunity for pharmacologic intervention to therapeutic benefit. Unfortunately, many classes of oncoproteins (e.g., transcription factors) are not amenable to conventional small-molecule screening. Des...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Stegmaier, Kimberly, Wong, Jenny S, Ross, Kenneth N, Chow, Kwan T, Peck, David, Wright, Renee D, Lessnick, Stephen L, Kung, Andrew L, Golub, Todd R
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2007
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851624/
https://ncbi.nlm.nih.gov/pubmed/17425403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040122
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन