Relative activities of acyclovir and BW759 against Aujeszky's disease and equine rhinopneumonitis viruses.

Compound BW759 (9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine) was shown to be about 230 times more active than acyclovir (9-[2-hydroxyethoxymethyl]guanine) (ACV) against Equid herpesvirus type 1 infection in Syrian hamsters and was more effective against Aujeszky's disease in mice. The therape...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Rollinson, E A, White, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6314886/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.2.221
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