Pharmacokinetics of metioprim in normal subjects and patients with impaired renal function.

The pharmacokinetics of metioprim, a new competitive inhibitor of bacterial dihydrofolate reductases, were studied after a single oral dose of 100 mg in two young healthy subjects, four elderly volunteers, and eight patients with impaired renal function. The pharmacokinetic parameters of unchanged m...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Vergin, H, Bishop-Freudling, G B, Kaiser, W, Köhler, M, Strobel, K, Reutter, F W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6638987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.2.190
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