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Pharmacokinetics of metioprim in normal subjects and patients with impaired renal function.

The pharmacokinetics of metioprim, a new competitive inhibitor of bacterial dihydrofolate reductases, were studied after a single oral dose of 100 mg in two young healthy subjects, four elderly volunteers, and eight patients with impaired renal function. The pharmacokinetic parameters of unchanged m...

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Détails bibliographiques
Auteurs principaux: Vergin, H, Bishop-Freudling, G B, Kaiser, W, Köhler, M, Strobel, K, Reutter, F W
Format: Artigo
Langue:Inglês
Publié: 1983
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC185136/
https://ncbi.nlm.nih.gov/pubmed/6638987
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