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Comparative evaluation of the pharmacokinetics of N-methylthiotetrazole following administration of cefoperazone, cefotetan, and cefmetazole.

The comparative pharmacokinetics and in vivo production of N-methylthiotetrazole (NMTT) were evaluated following administration of cefoperazone, cefotetan, and cefmetazole. In a randomized-crossover manner, 11 healthy male volunteers received single 2-g intravenous doses of each agent and serial blo...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Welage, L S, Borin, M T, Wilton, J H, Hejmanowski, L G, Wels, P B, Schentag, J J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2088192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.12.2369
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