CD21-Positive Follicular Dendritic Cells: A Possible Source of PrP(Sc) in Lymph Node Macrophages of Scrapie-Infected Sheep

Natural sheep scrapie is a prion disease characterized by the accumulation of PrP(Sc) in brain and lymphoid tissues. Previous studies suggested that lymph node macrophages and follicular dendritic cells (FDC) accumulate PrP(Sc). In this study, lymph nodes were analyzed for the presence of PrP(Sc) an...

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Hlavní autoři: Herrmann, Lynn M., Cheevers, William P., Davis, William C., Knowles, Donald P., O’Rourke, Katherine I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2003
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851249/
https://ncbi.nlm.nih.gov/pubmed/12651600
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