Loss of Expression of the WNT/β-Catenin-Signaling Pathway Transcription Factors Lymphoid Enhancer Factor-1 (LEF-1) and T Cell Factor-1 (TCF-1) in a Subset of Peripheral T Cell Lymphomas

T cell factor-1 (TCF-1) and lymphoid enhancer factor-1 (LEF-1), members of the TCF/LEF family of transcription factors, play a significant role in T cell development and are expressed in thymocytes and peripheral CD3+ T cells. Previously, precursor T lymphoblastic leukemia/lymphoblastic lymphoma (T-...

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Bibliographic Details
Main Authors: Dorfman, David M., Greisman, Harvey A., Shahsafaei, Aliakbar
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851202/
https://ncbi.nlm.nih.gov/pubmed/12707037
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