Increased Plasminogen Activator Inhibitor-1 in Keloid Fibroblasts May Account for their Elevated Collagen Accumulation in Fibrin Gel Cultures

Proteolytic degradation of the provisional fibrin matrix and subsequent substitution by fibroblast-produced collagen are essential features of injury repair. Immunohistochemical studies revealed that although dermal fibroblasts of normal scars and keloids expressed both urokinase type plasminogen ac...

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Detalhes bibliográficos
Main Authors: Tuan, Tai-Lan, Wu, Huayang, Huang, Eunice Y., Chong, Sheree S. N., Laug, Walter, Messadi, Diana, Kelly, Paul, Le, Anh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851185/
https://ncbi.nlm.nih.gov/pubmed/12707042
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