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Structural basis for ligand and heparin binding to neuropilin B domains
Neuropilin (Nrp) is a cell surface receptor with essential roles in angiogenesis and axon guidance. Interactions between Nrp and the positively charged C termini of its ligands, VEGF and semaphorin, are mediated by Nrp domains b1 and b2, which share homology to coagulation factor domains. We report...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851056/ https://ncbi.nlm.nih.gov/pubmed/17405859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700043104 |
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