A Mouse Model of Hepatocellular Carcinoma : Ectopic Expression of Fibroblast Growth Factor 19 in Skeletal Muscle of Transgenic Mice

Most mouse models of hepatocellular carcinoma have expressed growth factors and oncogenes under the control of a liver-specific promoter. In contrast, we describe here the formation of liver tumors in transgenic mice overexpressing human fibroblast growth factor 19 (FGF19) in skeletal muscle. FGF19...

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Detalhes bibliográficos
Main Authors: Nicholes, Katrina, Guillet, Susan, Tomlinson, Elizabeth, Hillan, Kenneth, Wright, Barbara, Frantz, Gretchen D., Pham, Thinh A., Dillard-Telm, Lisa, Tsai, Siao Ping, Stephan, Jean-Philippe, Stinson, Jeremy, Stewart, Timothy, French, Dorothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Animal Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850847/
https://ncbi.nlm.nih.gov/pubmed/12057932
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