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Metallothionein-Independent Zinc Protection from Alcoholic Liver Injury

Previous studies using metallothionein (MT)-overexpressing transgenic mice have demonstrated that MT protects the liver from oxidative injury induced by alcohol. The mechanism of action of MT is unknown. Because MT primarily binds to zinc under physiological conditions and releases zinc under oxidat...

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Detalhes bibliográficos
Main Authors: Zhou, Zhanxiang, Sun, Xiuhua, Lambert, Jason C., Saari, Jack T., Kang, Y. James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850821/
https://ncbi.nlm.nih.gov/pubmed/12057929
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