Metallothionein-Independent Zinc Protection from Alcoholic Liver Injury

Previous studies using metallothionein (MT)-overexpressing transgenic mice have demonstrated that MT protects the liver from oxidative injury induced by alcohol. The mechanism of action of MT is unknown. Because MT primarily binds to zinc under physiological conditions and releases zinc under oxidat...

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Autori principali: Zhou, Zhanxiang, Sun, Xiuhua, Lambert, Jason C., Saari, Jack T., Kang, Y. James
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850821/
https://ncbi.nlm.nih.gov/pubmed/12057929
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