Generation of C5a by Phagocytic Cells

The complement activation product, C5a, is a powerful phlogistic factor. Using antibodies to detect human or rat C5a, incubation at pH 7.4 of human blood neutrophils or rat alveolar macrophages (AMs) with C5 in the presence of phorbol 12-myristate 13-acetate (PMA) led to generation of C5a. Rat AMs a...

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Bibliographic Details
Main Authors: Huber-Lang, Markus, Younkin, Ellen M., Sarma, J. Vidya, Riedemann, Niels, McGuire, Stephanie R., Lu, Kristina T., Kunkel, Robin, Younger, John G., Zetoune, Firas S., Ward, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850785/
https://ncbi.nlm.nih.gov/pubmed/12414531
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