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CD40-CD40L Interactions Induce Chemokine Expression by Human Microglia : Implications for Human Immunodeficiency Virus Encephalitis and Multiple Sclerosis
CD40 is a protein on microglia that is up-regulated with interferon (IFN)-γ and is engaged by CD40L, found on CD4(+) T cells, B cells, and monocytes. These interactions may be important in central nervous system inflammatory diseases. Microglia have been shown to be a source of chemokines, whose exp...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Investigative Pathology
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850648/ https://ncbi.nlm.nih.gov/pubmed/11839576 |
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