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CD40-CD40 Ligand Interactions in Human Microglia Induce CXCL8 (Interleukin-8) Secretion by a Mechanism Dependent on Activation of ERK1/2 and Nuclear Translocation of Nuclear Factor-κB (NFκB) and Activator Protein-1 (AP-1)
CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV-1) encephalitis, but the mechanism of secretion of this chemokine is not fully understood. CD40...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2639790/ https://ncbi.nlm.nih.gov/pubmed/17918746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21525 |
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