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Quantitative Assessment of Promoter Hypermethylation during Breast Cancer Development

The aberrant methylation of cytosine residues in the promoter region of growth regulatory genes is now widely recognized as an additional mechanism for gene inactivation in cancer cells. In this study we analyzed the methylation status of four growth regulatory genes (p16, RASSF1A, cyclinD2, 14-3-3ς...

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Hlavní autoři: Lehmann, Ulrich, Länger, Florian, Feist, Henning, Glöckner, Sabine, Hasemeier, Britta, Kreipe, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850646/
https://ncbi.nlm.nih.gov/pubmed/11839581
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