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Quantitative Assessment of Promoter Hypermethylation during Breast Cancer Development

The aberrant methylation of cytosine residues in the promoter region of growth regulatory genes is now widely recognized as an additional mechanism for gene inactivation in cancer cells. In this study we analyzed the methylation status of four growth regulatory genes (p16, RASSF1A, cyclinD2, 14-3-3ς...

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Autori principali: Lehmann, Ulrich, Länger, Florian, Feist, Henning, Glöckner, Sabine, Hasemeier, Britta, Kreipe, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850646/
https://ncbi.nlm.nih.gov/pubmed/11839581
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