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Detection of Gene Amplification in Archival Breast Cancer Specimens by Laser-Assisted Microdissection and Quantitative Real-Time Polymerase Chain Reaction

Gene amplification is one of the most important mechanisms leading to deregulated gene expression in cancer. The exact quantitative detection of this frequent genomic alteration in solid tumors is often hampered by an admixture of nonneoplastic bystander and stroma cells. To overcome this obstacle a...

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Detalhes bibliográficos
Main Authors: Lehmann, Ulrich, Glöckner, Sabine, Kleeberger, Wolfram, von Wasielewski, Henning Feist Reinhard, Kreipe, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850085/
https://ncbi.nlm.nih.gov/pubmed/10854209
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