Loss of CDX2 Expression and Microsatellite Instability Are Prominent Features of Large Cell Minimally Differentiated Carcinomas of the Colon

Most large bowel cancers are moderately to well-differentiated adenocarcinomas comprised chiefly or entirely of glands lined by tall columnar cells. We have identified a subset of poorly differentiated colon carcinomas with a distinctive histopathological appearance that we term large cell minimally...

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Bibliographische Detailangaben
Hauptverfasser: Hinoi, Takao, Tani, Masachika, Lucas, Peter C., Caca, Karel, Dunn, Rodney L., Macri&para, Ettore, Loda&para, Massimo, Appelman, Henry D., Cho, Kathleen R., Fearon, Eric R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2001
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850596/
https://ncbi.nlm.nih.gov/pubmed/11733373
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