Role of CD40-CD40L in Mouse Severe Malaria

We explored the role of CD40-CD40L (CD154) in the severe malaria elicited by Plasmodium berghei anka infection in mice. Mortality was >90% by day 8 after infection in +/+ mice, but markedly decreased in CD40−/− or in CD40L−/− mice, as well as in +/+ mice treated with anti-CD40L monoclonal antibod...

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Autores principales: Piguet, Pierre Francois, Da Kan, Chen, Vesin, Christian, Rochat, Anne, Donati, Yves, Barazzone, Constance
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2001
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850550/
https://ncbi.nlm.nih.gov/pubmed/11485931
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