PTEN Is a Target of Chromosome 10q Loss in Anaplastic Oligodendrogliomas and PTEN Alterations Are Associated with Poor Prognosis

Allelic loss of 10q is a common genetic event in malignant gliomas, with three 10q tumor suppressor genes, ERCC6, PTEN, and DMBT1, putatively implicated in the most common type of malignant glioma, glioblastoma. Anaplastic oligodendroglioma, another type of malignant glioma, provides a unique opport...

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Main Authors: Sasaki, Hikaru, Zlatescu, Magdalena C., Betensky, Rebecca A., Ino, Yasushi, Cairncross, J. Gregory, Louis, David N.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850425/
https://ncbi.nlm.nih.gov/pubmed/11438483
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