Alteration of Transforming Growth Factor-β1 Response Involves Down-Regulation of Smad3 Signaling in Myofibroblasts from Skin Fibrosis

Fibrosis is an unregulated tissue repair process whose predominant characteristics are the proliferation of myofibroblasts and an excessive deposition of extracellular matrix. Transforming growth factor (TGF)-β1 is considered as one of the most fibrogenic cytokines. However, the molecular mechanisms...

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Bibliografiska uppgifter
Huvudupphovsmän: Reisdorf, Philippe, Lawrence, David. A., Sivan, Virginie, Klising, Eve, Martin, Michèle T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2001
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850409/
https://ncbi.nlm.nih.gov/pubmed/11438473
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