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Protein oxidation in response to increased transcriptional or translational errors

In this study, we show a correlation between synthesis of aberrant proteins and their oxidative modification. The level of aberrant proteins was elevated in Escherichia coli cultures by decreasing transcriptional or translational fidelity using specific mutations or drugs. Protein carbonylation, an...

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Bibliographic Details
Main Authors: Dukan, S., Farewell, A., Ballesteros, M., Taddei, F., Radman, M., Nyström, T.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18504/
https://ncbi.nlm.nih.gov/pubmed/10811907
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