Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer

An acidic extracellular pH is a fundamental property of the malignant phenotype. In von Hippel-Lindau (VHL)-defective tumors the cell surface transmembrane carbonic anhydrase (CA) CA9 and CA12 genes are overexpressed because of the absence of pVHL. We hypothesized that these enzymes might be involve...

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Detalhes bibliográficos
Main Authors: Ivanov, Sergey, Liao, Shu-Yuan, Ivanova, Alla, Danilkovitch-Miagkova, Alla, Tarasova, Nadezhda, Weirich, Gregor, Merrill, Marsha J., Proescholdt, Martin A., Oldfield, Edward H., Lee, Joshua, Zavada, Jan, Waheed, Abdul, Sly, William, Lerman, Michael I., Stanbridge, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850340/
https://ncbi.nlm.nih.gov/pubmed/11238039
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