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The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain

The Nova family of proteins are target antigens in the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia and contain K-homology (KH)-type RNA binding domains. The Nova-1 protein has recently been shown to regulate alternative splicing of the α2 glycine receptor subunit pre-mRNA by bindi...

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Autors principals: Jensen, Kirk B., Musunuru, Kiran, Lewis, Hal A., Burley, Stephen K., Darnell, Robert B.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18503/
https://ncbi.nlm.nih.gov/pubmed/10811881
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