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Immune Complex Formation after Xenotransplantation : Evidence of Type III as well as Type II Immune Reactions Provide Clues to Pathophysiology

Rejection of renal and cardiac xenografts is initiated when natural antibodies of the recipient bind to donor endothelium, activating complement on the surface of endothelial cells. Pulmonary xenotransplants, however, reveal less evidence of antibody binding and complement activation and, in contras...

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Autori principali: Holzknecht, Zoie E., Coombes, Sarah, Blocher, Brian A., Plummer, Timothy B., Bustos, Matilde, Lau, Christine L., Davis, R. Duane, Platt, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850294/
https://ncbi.nlm.nih.gov/pubmed/11159199
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