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Immune Complex Formation after Xenotransplantation : Evidence of Type III as well as Type II Immune Reactions Provide Clues to Pathophysiology

Rejection of renal and cardiac xenografts is initiated when natural antibodies of the recipient bind to donor endothelium, activating complement on the surface of endothelial cells. Pulmonary xenotransplants, however, reveal less evidence of antibody binding and complement activation and, in contras...

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Detalhes bibliográficos
Main Authors: Holzknecht, Zoie E., Coombes, Sarah, Blocher, Brian A., Plummer, Timothy B., Bustos, Matilde, Lau, Christine L., Davis, R. Duane, Platt, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850294/
https://ncbi.nlm.nih.gov/pubmed/11159199
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