Interferon-γ Acts Directly on Rejecting Renal Allografts to Prevent Graft Necrosis

In transplant rejection interferon (IFN)-γ regulates the recipient immune response but also acts directly on IFN-γ receptors in the graft. We investigated these direct actions by comparing rejecting kidneys from donors lacking IFN-γ receptors (GRKO mice) or control donors (129Sv/J) in CBA recipients...

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Main Authors: Halloran, Philip F., Afrouzian, Marjan, Ramassar, Vido, Urmson, Joan, Zhu, Lin-Fu, Helms, Lisa M. H., Solez, Kim, Kneteman, Norman M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2001
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850268/
https://ncbi.nlm.nih.gov/pubmed/11141495
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