Angiotensin II (AT(1)) Receptor Blockade Reduces Vascular Tissue Factor in Angiotensin II-Induced Cardiac Vasculopathy

Tissue factor (TF), a main initiator of clotting, is up-regulated in vasculopathy. We tested the hypothesis that chronic in vivo angiotensin (ANG) II receptor AT(1) receptor blockade inhibits TF expression in a model of ANG II-induced cardiac vasculopathy. Furthermore, we explored the mechanisms by...

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Hauptverfasser: Müller, Dominik N., Mervaala, Eero M. A., Dechend, Ralf, Fiebeler, Anette, Park, Joon-Keun, Schmidt, Folke, Theuer, Jürgen, Breu, Volker, Mackman, Nigel, Luther, Thomas, Schneider, Wolfgang, Gulba, Dietrich, Ganten, Detlev, Haller, Hermann, Luft, Friedrich C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850216/
https://ncbi.nlm.nih.gov/pubmed/10880382
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