Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors : A Study of 200 Cases

Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, typically express the KIT protein. Activating mutations in the juxtamembrane domain (exon 11) of the c-kit gene have been shown in a subset of GISTs. These mutations lead into ligand-independen...

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Autores principales: Lasota, Jerzy, Wozniak, Agnieszka, Sarlomo-Rikala, Maarit, Rys, Janusz, Kordek, Radzislaw, Nassar, Aziza, Sobin, Leslie H., Miettinen, Markku
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2000
Materias:
Short Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850182/
https://ncbi.nlm.nih.gov/pubmed/11021812
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