Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

Gastrointestinal stromal tumors (GISTs) comprise the largest subset of mesenchymal tumors of the gastrointestinal tract. These neoplasms differ histologically and immunohistochemically from typical leiomyomas and leiomyosarcomas. Most GISTs express CD34 and CD117 (c-kit protein) but not desmin. Rece...

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Autores principales: Lasota, Jerzy, Jasinski, Marek, Sarlomo-Rikala, Maarit, Miettinen, Markku
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1999
Materias:
Short Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853448/
https://ncbi.nlm.nih.gov/pubmed/9916918
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