α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress

Abnormal accumulation of the presynaptic protein α-synuclein has recently been implicated in the pathogenesis of Alzheimer’s and Parkinson’s diseases. Because neurodegeneration in these conditions might be associated with mitochondrial dysfunction and oxidative stress, the effects of α-synuclein wer...

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Main Authors: Hsu, Leigh J., Sagara, Yutaka, Arroyo, Armando, Rockenstein, Edward, Sisk, Abbyann, Mallory, Margaret, Wong, Jeff, Takenouchi, Takato, Hashimoto, Makoto, Masliah, Eliezer
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2000
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850140/
https://ncbi.nlm.nih.gov/pubmed/10934145
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